Vosoritide的成功，再次向外界证明了罕见病赛道的巨大潜力：ACH看似是罕见病，但明确的致病机制、典型的临床表现，叠加数万级的患者基数和迫切、长期的治疗需求，使其成为了一个极具开发价值的 “不罕见” 罕见病市场。
icon-to-image#As someone who primarily works in Python, what first caught my attention about Rust is the PyO3 crate: a crate that allows accessing Rust code through Python with all the speed and memory benefits that entails while the Python end-user is none-the-wiser. My first exposure to pyo3 was the fast tokenizers in Hugging Face tokenizers, but many popular Python libraries now also use this pattern for speed, including orjson, pydantic, and my favorite polars. If agentic LLMs could now write both performant Rust code and leverage the pyo3 bridge, that would be extremely useful for myself.
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Journals that focus on specific research questions could help to bridge the science–policy gap, if they can attract researchers.